Variation in the IgG subclass structures shapes the biological effector activities, in broad terms, IgG1 and IgG3 are more potent in inducing these effector functions, while IgG2 and IgG4 do less so.

Researchers are studying a new approach to HDFN prevention to reduce cases in countries where incidence rates remain high.

In the past decade, many novel concepts to generate bispecific and multispecific antibodies have evolved successfully into a range of formats from full bispecific immunoglobulin gammas to antibody ...

Objective IgG4-related disease (IgG4-RD) is a heterogeneous, multiorgan condition of unclear aetiology that can cause organ failure. Difficulty recognising IgG4-RD contributes to diagnostic delays. We ...

HOUSE, Pa. - Johnson & Johnson (NYSE: NYSE:JNJ) has released new data on nipocalimab, an investigational drug with potential to treat diseases driven by immunoglobulin G (IgG) antibodies. Published in ...

The Vivacity-MG3 study is currently in its open-label extension phase, which is investigating the longer-term safety and ...

Objectives Hypocomplementaemia is common in patients with IgG4-related disease (IgG4-RD). We aimed to determine the IgG4-RD features associated with hypocomplementaemia and investigate mechanisms of ...

However, the study provides limited new insights into the relationship between retinal lamination defects and overall retinal function. Neural lamination is a common feature of the central nervous ...

February 11, 2025: We checked for new FC Mobile codes to get some extra cash and goodies in the game. These FC Mobile codes can help take your football career from Wembley to the worldwide scene with ...

Although the polymeric immunoglobulin receptor ... Azuma, Science University, Tokyo), and human IgM-Fc (Rockland, Gilbertsville, PA) were used. Monoclonal antibodies to human CD3, CD45 and ...