In the mouse developing embryo, she previously demonstrated a bias at the two-cell stage: one cell contributed more to fetal tissue and the other to the placenta. 4 “We know so little about the very ...

To answer this question, Hanna and his team set out to develop an ex utero embryo model. The team differentiated the human naïve ESC into four subpopulations and cultured them at specific ratios to ...

Early embryo development involves dramatic changes in epigenetic and transcriptional landscapes. How are these changes orchestrated in early human development? How is the oocyte reprogrammed to a ...