为解决肥厚性疤痕和瘢痕疙瘩形成机制不明的问题，韩国科学技术院的研究人员开展 hox 基因与机械力对疤痕形成影响的研究。结果发现张力稳态和 hox 基因影响疤痕形成。该研究为防治异常疤痕提供新思路，值得科研读者一读。

不同病理组织成纤维细胞的 hox 基因表达：研究人员在多种原发性和转移性肿瘤以及其他病理组织来源的 cafs 中评估 hox 基因表达模式。 结果发现，来自中胚层起源组织的病理组织成纤维细胞，包括 CAFs，都表现出高表达的 HOX 基因；而外胚间充质依赖区域肿瘤来源的 CAFs 则缺乏 HOX 基因表达，少数 ...

Hox genes and their relatives are involved in several developmental processes in diverse animals, but when did they first arise? The genome sequence of the sponge Amphimedon queenslandica shows ...

The Hox genes (also known as homeotic genes) play a crucial role in the development of animals, being involved in the determination of segment identity along the body axis. These genes were ...

Hox genes as architects of the body. Nearly all animals -- from humans to birds to fish -- have an anterior-posterior axis, or a line that runs from head to tail.

Hox genes control the identity of each vertebra during embryonic development in mammals, while the epigenetic regulator prevents these genes from being activated too soon.. In this study, the ...

Hox genes are famous for specifying body regions and their boundaries, such as the head, thorax and abdomen of insects, or the cervical, thoracic and lumbar vertebrae of mammals.

Hox genes | 3 min read. Mouse Stem Cells Made to Form Embryo-Like Structures. With just a molecular nudge, aggregates of embryonic stem cells take shape as a “gastroloid,” bearing the genetic ...

HOX proteins act like the body's "zip code," specifying the position of limbs in the fetus by encoding instructions for transcription factors, which attach to DNA and influence the action of genes.

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