Dec. 10, 2024 — In a single IV injection, a gene therapy targeting cBIN1 can reverse the effects of heart failure and restore heart function in a large animal model. The therapy increases the ...

Gene regulation refers to the mechanisms that act to induce or repress the expression of a gene. These include structural and chemical changes to the genetic material, binding of proteins to ...

In 1958, Francis Crick's sequence hypothesis finally provided an answer to the question: what is a gene? Why is this definition now considered overly simplistic? Roberts and Sharp also noted that ...

Edited by James Giovannoni, Boyce Thompson Institute for Plant Research, Ithaca, NY; received November 3, 2024; accepted January 9, 2025 ...

No. 11756050, Invitrogen, USA). Quantitative real time-PCR (qRT-PCR) was performed to quantify the levels of PAX3 and MITF using gene-specific primers and PowerUp SYBR Green Master Mix (Cat. No.