The HMGB1 primer sequences were: sense 5′-CAC CGT GGG ACT ATT AGG AT-3′ and antisense ... used to detect nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) activity using an NF-κB ...

Cardiac hypertrophy constitutes the primary pathological basis for heart failure and exerts a considerable influence on morbidity and mortality. Deubiquitinating enzymes are crucial regulators of ...

Deep in the Colombian Amazon, a team of scholars worked with Indigenous elders to interpret a 12-mile-long stretch of 11,000-year-old rock art. Researchers now believe that the art tells a ...

HMGB1 that belongs to the High Mobility Group-box superfamily, is a nonhistone chromatin associated transcription factor. It is present in the nucleus of eukaryotes and can be actively secreted or ...

SAN FRANCISCO--(BUSINESS WIRE)--Motif, a startup founded in 2023 by design software luminaries Amar Hanspal and Brian Mathews, has secured $46 million in seed and Series A funding to develop a ...

SAN FRANCISCO, January 30, 2025--(BUSINESS WIRE)--Motif, a startup founded in 2023 by design software luminaries Amar Hanspal and Brian Mathews, has secured $46 million in seed and Series A ...

Motif, a startup founded in 2023 by design software luminaries Amar Hanspal and Brian Mathews, has secured $46 million in seed and Series A funding to develop a next-generation platform for buildings.

This work presents important findings regarding the interaction of the monkeypox virus (MPXV) attachment H3 protein with the cellular receptor heparan sulfate and the use of this information to ...

HMGB1 lacks signal peptide and utilizes diverse non-canonical secretion mechanisms ... Proteins in the HMGA family contain an AT-hook, which is a DNA-binding motif with a preference for A/T rich ...