Expression of MYH11, FN1, and α-SMA was also lower in the thoracic aorta, left renal artery, and superior mesenteric artery of rats overexpressing the lncRNA AK098656 gene, while collagen-I deposition ...

A major objective in farm animal production is to enhance meat yield and quality through the regulation of lncRNA expression. This involves developing strategies to harness lncRNAs, which are known to ...

A research team has identified the core gene expression networks regulated by key proteins that fundamentally drive phenomena such as cancer development, metastasis, tissue differentiation from ...

A research team at KAIST has identified the core gene expression networks regulated by key proteins that fundamentally drive phenomena such as cancer development, metastasis, tissue ...

Changes to the intermediate filament (IF) protein, vimentin, were found to promote tumor growth by increasing cancer stemness in an oestrogen independent manner. Targeting vimentin and/or the long ...

SRF is a transcription factor directly controlling the expression of at least 200–300 genes, regulating cell growth, proliferation, apoptosis, and motility, and is indispensable for organ ...

Here we show, in relevant cellular models of HBV replication, that HBx activates the expression and directly binds the lncRNA DLEU2 to modulate transcription from the HBV cccDNA minichromosome, hence ...

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Get Instant Summarized Text (Gist) A novel mechanism has been identified that eliminates defective transcriptional elongation enzymes during gene expression. This process involves the ARMC5 ...

Additional subtypes of myositis can be defined by the presence of myositis-specific autoantibodies (MSAs). The purpose of this study was to define unique gene expression profiles in muscle biopsies ...