This manuscript demonstrates that Oct4 overexpression synergizes with Notch inhibition (Rbpj knockout) to promote the conversion of adult murine Müller glia (MG) into bipolar cells. These findings are ...

研究涉及海马CA1区和内侧颞叶皮质，以及皮质投射神经元标记物Satb2和Nurr1、中间神经元标记物calretinin和胶质细胞标记物GFAP。结果显示，GR与calretinin的共定位系数最高。在地塞米松注射后6小时，GR与投射神经元标记物（也是转录因子）的共定位系数增加至与GR ...

Longitudinal increases in NfL and GFAP levels were associated with cognitive decline among patients with type 2 diabetes and obesity. Longitudinal increases in neurofilament light chain (NfL ...

Department of Neurology, Renmin Hospital of Wuhan University, Wuhan, China Anti-NMDAR encephalitis is the most common autoimmune encephalitis. When first-line treatments fail, second-line therapies ...

It also decreased astrocyte and microglia activation in the cortex and hippocampus of LPS+ Amb-treated mice, as indicated by the downregulation of GFAP and Iba-1. Furthermore, ambroxol-reversed ...

Non-transgenic littermates, JN4 or JN25 (WT4R) mice up to 10 months of age lacked these pathological changes; however, we found MC-1 (refs 11–13)–positive cell bodies in the cortex ...