Gene Ontology (GO) is a widely used bioinformatics resource for describing biological processes, molecular functions, and cellular components of proteins. It covers more than 5000 terms hierarchically ...

New research reveals how exercise transforms muscles into communication hubs that release beneficial molecules throughout the ...

Protein folding articles from across Nature Portfolio Atom RSS Feed Protein folding is the process by which proteins achieve their mature functional (native) tertiary structure, and often begins ...

More information: Peizhen Bai et al, Mask-prior-guided denoising diffusion improves inverse protein folding, Nature Machine Intelligence (2025). DOI: 10.1038/s42256-025-01042-6 ...

New research by Sumeda Nandadasa, Ph.D., reveals how a key protein associated with Meckel-Gruber syndrome, nephronophthisis, ...

Scientists have created an AI approach that could make designing proteins for new medicines easier. This new AI approach outperforms current methods for "inverse protein folding" – a critical part of ...

Protein analysis is the bioinformatic study of protein structure and function using database searches, sequence comparisons, structural and functional predictions.

Inverse protein folding is important but difficult because small changes in protein sequences can cause unpredictable effects on the protein's structure For medicines to work properly, proteins ...

Scientists have developed a technique that aligns stem cells into a single sheet, resulting in a marked increase in the secretion of signaling proteins which help repair tissue and regulate the immune ...

But do they function in vivo? To test whether their de novo protein designs could function in living systems, the team created active inhibitors targeting bacterial phage proteins. Typically ...

A strategy that analyzes the structural properties of RNA could help identify regions that are promising targets for antiviral drugs.

Citrate is essential for the metabolism and development of neurons. A membrane transport protein called SLC13A5 plays a ...