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This study provides proof-of-principle data for the use of trained immunity to modulate macrophage interactions with tumours. The study makes a valuable contribution to the field of trained immunity.

Cell apoptosis and cell cycle were analyzed by flow cytometry, and the levels of genes and proteins of the Raf/MEK/ERK pathway were determined by RT-PCR and Western blotting.

Mice with identical genetics and environmental exposures display different cancer risk profiles based on distinct epigenetic signatures.

Liver TET1 was found to promote metabolic dysfunction-associated steatotic liver disease (MASLD) by regulating CD36 ...

Glioblastoma multiforme (GBM), commonly referred to as glioblastoma, is a malignant intracranial tumor derived from glial ...