Iron-dependent ferroptosis, a non-apoptotic cell death mechanism, is gaining attention for its role in immune suppression.

Oxidative Stress: Neuropathy, Excitability, and Neurodegeneration.

已有研究表明，miR-34a-5p 参与细胞铁死亡（ferroptosis）的调控。此次研究旨在探索 miR-34a-5p 在 ... 而 SIRT1、谷胱甘肽过氧化物酶 4（GPX4）、铁蛋白（Ferritin）和谷胱甘肽（GSH）的表达水平则上调。miR-34a-5p 可能通过直接靶向 SIRT1，调控参与神经元铁死亡的 Wnt/β-catenin ...

Hepatocellular carcinoma (HCC) represents the most prevalent form of liver cancer. Despite notable advancements in therapeutic strategies, HCC continues to pose significant public health challenges ...