Using a series of more than 1,000 X-ray snapshots of the shapeshifting of enzymes in action, researchers at Stanford ...

Unfortunately, there isn't an enzyme for many reactions we would sorely like to catalyze—things like digesting plastics or ...

New research uses AI to engineer enzymes with intricate active sites, expanding the possibilities for synthetic biocatalysts.

New research represents a notable step forward in designing enzymes from scratch. With their approach, the authors designed an enzyme that uses a ...

New research represents a notable step forward in designing enzymes from scratch. With their approach, the authors designed an enzyme that uses a covalent intermediate to catalyze a two-step reaction, ...

Alphamab Oncology (Stock Code: 9966.HK) and CSPC Pharmaceutical Group Co., Ltd. ('CSPC') (Stock Code: 1093.HK) jointly announced that anti-HER2 biparatopic antibody-drug conjugate (ADC) JSKN003 has ...

Ecovyst Inc. (NYSE: ECVT), a leading integrated and innovative global provider of advanced materials, specialty catalysts, sulfuric acid and regeneration services ("Ecovyst"), and ChiralVision B.V., a ...

The mechanism of enzyme catalysis is similar in principle to other types of chemical catalysis, for instance by involving a combination of several different types of catalysis. Determining enzyme ...

The DNA library was generated using PCR, Gibson assembly, and iterative site saturation mutagenesis ... The method significantly enhanced enzyme activity, providing a scalable, high-throughput ...

Researchers from Zhejiang University and HKUST (Guangzhou) have developed a cutting-edge AI model, ProtET, that leverages multi-modal learning to enable controllable protein editing through text-based ...

However, if an inhibitor is present and catalysis does not take place, the enzyme does not reassociate for at least 180 min, as can be seen in Figure S6. This leads us to conclude that as long as a ...

Their high-resolution structural studies, combined with computational analysis and site-directed mutagenesis ... demonstrates how nature has evolved elegant solutions for coordinating multiple ...