An expert review provides best practice advice on diagnostic considerations of immune-mediated disorders that should be ...

Rationale The pathogenesis of EoE is uncertain, but it is known that eosinophils contain mediators associated with tissue remodeling and the development of fixed fibrosis. An undetermined portion ...

The authors recommend that EoE is diagnosed based on the presence of symptoms of esophageal dysfunction and at least 15 eosinophils per high-power field on esophageal biopsy. A systematic endoscopic ...

Endoscopy with biopsy is currently the only method to assess oesophageal mucosal inflammation in EoE. We hypothesised that measurements of luminal eosinophil-derived proteins would correlate with ...

endoscopic appearance or the excess of eosinophilic concentration. Maximizing the report of the biopsies with an accurate assessment of all histological features is therefore of the utmost importance ...

By proteomic profiling of routine diagnostic FFPE biopsy specimens (n = 55) representing controls, Reflux- (GERD), Eosinophilic-(EoE), Crohn’s-(CD), Herpes simplex (HSV ... However, partially ...

Suggested treatments for eosinophilic esophagitis include proton pump inhibitors, topical steroids, empiric food elimination diet, biologics, endoscopic dilation. HealthDay News — In a clinical ...

A systematic endoscopic scoring system is recommended to characterize endoscopic findings of EoE at every endoscopy. To assess for histologic features consistent with EoE, at least 6 esophageal ...

There are significant seasonal and temporal variation in eosinophilic esophagitis-related emergency department visits across all regions in the United States. Seasonal trends in emergency department ...

A recent retrospective cohort study by Lee and Dellon (159) included 46 adults patients treated with dupilumab for severe, refractory, fibro-stenotic EoE. After a median of 6 months of dupilumab ...