Generally, the pathophysiology of schizophrenia is believed to be determined by imbalances in neurotransmitters, in particular dopamine and serotonin, and in four neural pathways in the brain ...

Medications that are currently available for schizophrenia generally target dopamine and are usually ... use genetic data to connect neural pathways with symptoms. In a world where identifying ...

Feb. 19, 2025 — A genetic mutation found in two human patients with schizophrenia also increased schizophrenia-related behaviors in mice with the same mutation, a rare finding of a direct ...

Historically, most antipsychotic drugs for schizophrenia have targeted dopamine pathways, specifically the D2 receptors, to manage symptoms. However, this approach has limitations, as many ...