2,6-Disubstituted dihydropyrans are a common feature in many bioactive polyketides, including the anticancer marine polyketide laulimalide. While much of the uncharacterized biosynthetic pathway for ...

The chemical structures of the new compounds were elucidated by means of NMR (COSY, HSQC, HMBC and NOESY) and HRMS spectral ... (d, J 8.6, 2H), suggested the existence of a para-disubstituted benzene ...

Solution-state nuclear magnetic resonance (NMR) spectroscopy is the classical NMR spectroscopy approach used for molecular structure determination, where the experimental sample is studied while ...

IN view of the projected celebration of the centenary of Faraday's discovery of benzene in 1825, it is important that any doubt concerning his priority should be dispelled. The standard work on ...

Reactivity of 1,3-disubstituted indolyl compounds with lithium reagents was studied to reveal the substituents and solvent effects on coordination modes and reactivities resulting in different indolyl ...

RESULTS AND DISCUSSION Chemistry. Final compounds listed in Table I were synthesized using the sequence of reactions depicted in Figure 1.In the first step, compound I derivatives were prepared via ...