To approximate the desired structure, suitable RNA motifs must be selected and translated into a genetic template that is ultimately synthesized as an artificial gene. To implement the blueprint ...

Alternative splicing (AS) of pre-mRNA plays a crucial role in tissue-specific gene regulation, with disease implications due to splicing defects. Predicting and manipulating AS can therefore uncover ...

engineering and cleavage site requirements for each of these ribozyme motifs are different. For anyone interested in using a ribozyme to inactivate a given RNA target, there is no simple formula ...

and to quantify the changing expression levels of each transcript during development and under different conditions. “RNA-Seq [...] is expected to revolutionize the manner in which eukaryotic tr ...

To approximate the desired structure, suitable RNA motifs must be selected and translated into a genetic template that is ultimately synthesized as an artificial gene. To implement the blueprint ...

By discovering new ways to manipulate matter at the atomic and molecular levels, advances in nanotechnology are paving the way for innovations in medicine, electronics, materials science and ...

The rRNA molecules fold into complex secondary and tertiary structures, forming domains and motifs that are essential for ribosome ... This discovery led to the concept of the ribosome as a ribozyme, ...

Zhang's team discovered over 20,000 different Tas proteins, mostly occurring in bacteria-infecting viruses. Sequences within ...