This manuscript demonstrates that Oct4 overexpression synergizes with Notch inhibition (Rbpj knockout) to promote the conversion of adult murine Müller glia (MG) into bipolar cells. These findings are ...

Single-Molecule Footprinting reveals that RNA polymerase II (Pol II) occupancy is infrequent at mouse promoters. This results ...

How cardiac cell fates are specified during heart development remains elusive. This study identifies a level-dependent role ...

Alternative splicing (AS) of pre-mRNA plays a crucial role in tissue-specific gene regulation, with disease implications due to splicing defects. Predicting and manipulating AS can therefore uncover ...

To approximate the desired structure, suitable RNA motifs must be selected and translated into a genetic template that is ultimately synthesized as an artificial gene. To implement the blueprint ...

To approximate the desired structure, suitable RNA motifs must be selected and translated into a genetic template that is ultimately synthesized as an artificial gene. To implement the blueprint ...

It codes for the shape that the RNA should assume after folding. To approximate the desired structure, suitable RNA motifs must be selected and translated into a genetic template that is ultimately ...

In her latest comedy special, “A Different Animal,” which premiered on Tuesday on Prime Video, Shlesinger dives into her evolution as a mother of two dealing with “mom brain” while proudly ...

Brinda Dudhat, the founder of Morii Design in India, creates modern motifs supported by age-old techniques. By Sarah Archer This article is part of our Design special section about the reverence ...

5-甲基胞嘧啶（m 5 C）修饰是RNA最普遍的修饰之一。m 5 C修饰通过影响RNA出核、稳定和剪接等过程来参与多种生物学功能。造血干祖细胞为支持生命持续，分化为各种类型的血细胞，是维持血液系统正常功能的核心细胞。造血干祖细胞在发育过程中经历快速的全局 ...