Understanding the reprogramming of gene expression and metabolism is critical for the success of somatic embryogenesis-based plant tissue regeneration. Here, the authors report single-cell RNA ...

In a study published in Nature Structural and Molecular Biology, scientists from the Department of Medical Biochemistry and ...

They suggest that genetically equivalent neurons can become functionally and morphologically different during differentiation ... might not greatly affect gene expression. Cellular atlases ...

Organoids were cultured from healthy donor iPSC sources and differentiated using the human iPSC-derived Cerebral Organoid ...

A single gene in the shorebird species known as ruffs controls the levels of testosterone in males, and this in turn affects ...

Oxytocin receptor (Oxtr) signaling influences complex social behaviors in diverse species, including social monogamy in prairie voles. How Oxtr regulates specific components of social attachment ...

Many studies have used single-cell RNA sequencing (scRNA-seq) to infer gene regulatory networks (GRNs), which are crucial for ...

This important study demonstrates the potential of synthetic gene circuits to detect and target aberrant RAS activity in cancer cell lines. The circuit design is novel and the evidence supporting the ...

Congenital heart disease (CHD) affects approximately 1% of live births. Thanks to surgical advancements, infants born with ...

Combined differentially expressed genes and expression quantitative trait loci analysis was conducted to find key driver genes in SLE pathogenesis. Conclusion This work elucidated the potential ...

In a recently published study in Nature Structural and Molecular Biology, scientists from the Department of Medical ...

For patients with psychiatric conditions from addiction to mood disorders such as depression, disrupted sleep can often exacerbate symptoms and make it harder to stay on treatment.