A groundbreaking study published in the British Journal of Psychiatry shone a light on treatment-resistant depression (TRD), a condition that affects 48% of people with MDD. TRD is not just about ...

Ketamine has promise as a potential treatment for bipolar depression, particularly for people whose condition hasn’t ...

Bipolar disorder is a mental health condition marked by large shifts in mood from mania to depression. Although bipolar disorder can be challenging to manage, many effective treatments are available.

Astrocytes in the prefrontal cortex are closely linked to depression, but the underlying mechanisms remain unclear. Here, the authors show that reduction of astrocytic pleiotrophin in the ...