为探究黄病毒免疫机制,助力泛黄病毒疫苗研发,研究人员开展寨卡病毒(ZIKV)和登革病毒(DENV)对人树突状细胞(DC)影响的研究。结果发现 ZIKV 抑制 DC 成熟和 T 细胞激活,而 DENV 则激活 DC。这为理解病毒致病机制和疫苗设计提供关键依据。
The “disease of mechanics” concept extends beyond Dengue, offering parallels to other viral infections characterized by vascular dysfunction, such as Zika virus and Ebola virus. Comparative studies ...