B lymphocytes can regulate dendritic cell (DC) functions, but the extent of this regulation and the functional outcomes have not been fully established. Here, the authors show that direct ...

Dendritic cells (DCs) are the professional antigen-presenting cells of the immune system, with the potential to either stimulate or inhibit immune responses. Exploiting the immune-regulatory ...

Influenza hemagglutinin subunit vaccines are more effective and offer better cross protection against various influenza virus ...

In eight tumors where patients failed immune checkpoint inhibitor (ICI) treatment, Plinabulin + radiation + PD-1 inhibitors demonstrated ...

Blastic plasmacytoid dendritic-cell neoplasm (BPDCN) is an aggressive hematologic cancer that confers a predisposition to leukemic transformation and poor outcomes. 1 The exact incidence of BPDCN ...

New avenues for the optimzation of dendritic cell-based cancer immunotherapies. ScienceDaily . Retrieved May 16, 2025 from www.sciencedaily.com / releases / 2021 / 10 / 211012091855.htm ...

Survivin Dendritic Cell Vaccine Safely Induces Immune Responses and Is Associated with Durable Disease Control after Autologous Transplant in Patients with Myeloma. Clinical Cancer Research , 2023 ...

Dendritic cells (DCs) play a pivotal role in the cancer-immunity cycle by priming and activating antigen-specific effector T cells. 7,8 However, DCs are often excluded from PDAC tumors 9; hence, they ...

Autoimmune diseases: Abnormal dendritic cell activation and presentation of self-antigens may contribute to autoimmune diseases like rheumatoid arthritis, lupus erythematosus, autoimmune myocarditis, ...

Diakonos Oncology reports that an interim analysis of a Phase I open label trial of its dendritic cell vaccine (DOC1021) showed substantially increased survival of glioblastoma multiforme (GBM ...

A 62-year-old woman presented with a large necrotic plaque on her left cheek that was confirmed on biopsy to be a classic blastic plasmacytoid dendritic-cell neoplasm (Figure 1A and 1B).Positron ...

Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a type of blood cancer that affects immune system cells. It most often affects the skin but can also involve bone marrow and other cell types.