Since the COVID-19 pandemic, pretty much everybody is familiar with this technology: paper-based rapid test strips, also ...

“This idea evolved into the notion that if you have two primers that are interacting with recombinase proteins and they move in opposite directions along a double-stranded piece of DNA, wouldn’t you ...

A team of scientists has created a new guide to advance standards for collecting and cataloging DNA from marine species, ...

worked on refining DNA testing techniques. In the early 1990s, the FBI had begun exploring STR markers, whose short, two- to six-base pair sequences made them more efficient with PCR, which provided ...

1| Add 0.001–100 ng of poly(A) + mRNA or 0.01–1 μg of total RNA into each of three microcentrifuge tubes. Adjust the volumes to 9 μl with water. Denature the RNA by heating at 75 °C for 5 ...

This is done without the need for nucleic acid amplification. In CRISPR/Cas-based diagnostic tests, guide RNAs bind pathogen DNA or RNA, triggering Cas enzymes to become active and cleave the ...

A DNA nanomachine selectively targets skin cancer by detecting microRNA-7, activating phototherapy and releasing chemotherapy ...

Their CRISPR-Cascade reaction utilizes two ribonucleoprotein complexes, T1 and T2, to achieve amplification-free detection of pathogenic DNA. Upon target recognition, Cas12a in the T1 complex ...