Hyperplastic glands comprise largely unperturbed fibroblasts but include an expanded CRABP1 + subset. Similar heterogeneity occurs amongst cancer-associated fibroblasts (CAFs) in different mammary ...

Combined clinical-stage company benefits from a strong pipeline: MOv18 IgE, an anti-Folate Receptorα IgE antibody, currently in a Phase Ib Proof of Concept trial in platinum-resistant ovarian cancer.

We collaborate with the world's leading lawyers to deliver news tailored for you. Sign Up for any (or all) of our 25+ Newsletters. Some states have laws and ethical rules regarding solicitation ...

A novel cell therapy approach using cord blood-derived natural killer (NK) cells pre-complexed with AFM13, or acimtamig, a CD30/CD16A bispecific antibody, was safe and generated strong response ...

This valuable study reports the critical role of two cyclin-dependent kinases, CDK8 and CDK19, in spermatogenesis. The data presented are generally supportive of the main conclusion and are considered ...

If both genetic parents are Rh-negative, their children will be, too. The pregnant parent should have their blood type, including Rh factor, tested and antibody screening done if indicated as part of ...

In the rapidly evolving field of antibody drug discovery, the ability to efficiently characterize and screen antibodies and antibody drug conjugates (ADCs) is crucial for developing effective ...

But promising results from a recent clinical trial suggest that broadly neutralizing antibody therapy (bNAbs) may be able to accomplish the next best thing. Data from the trial—a collaboration ...

The same cells transfected with a plasmid containing CRABP1 or LIMCH1 were used as positive control of staining and to assess antibody specificity. Cells were rinsed twice with distilled water and ...