If you're studying genetics, molecular biology or a related field, odds are good that you will need to learn how to read a codon chart (aka codon table) to better understand the genetic code. This ...

To overcome the inherent challenge of translation termination interference caused by stop codon reprogramming in mammalian ...

Amino acids are the building blocks of proteins. There are 20 different ones your body needs. Your body can make 11 of them. But you need to get the other nine from your diet. Those nine you need ...

Recently, researchers aiming to add completely new amino acids to a protein have created strategies to reassign a codon. For ...

“The assignment of the genetic code has some inherent malleability, which one can change to assign existing codons to new amino acids,” said Badran. His team leveraged this by using a plug-and-play ...

To overcome the inherent challenge of translation termination interference caused by stop codon reprogramming in mammalian ...

Living organisms synthesize a staggering variety of proteins by combining 20 amino acids into chains of any length and order. In the past, to expand protein diversity beyond the scope of these 20 ...

Now, scientists at Scripps Research have designed a new paradigm for easily adding non-canonical amino acids to proteins. Their approach, described in Nature Biotechnologyon September 11, 2024 ...

Recently, researchers aiming to add completely new amino acids to a protein have created strategies to reassign a codon. For instance, the UAU codon could be linked to a new amino acid by changing ...

Amino acids can catalyze RNA polymerization under mild, prebiotic conditions, increasing RNA formation by up to 100-fold through acid-base catalysis involving their amine groups.