Ephraim’s complaint against Gideon; kings of Midian slain; Gideon’s children; his death; Abimelech made king: death of Abimelech. And Gideon said unto them, I will not rule over you, neither shall my ...

Generative Phosphoproteomics AP3 platform designed to enable streamlined, rational drug discovery, with proprietary, proteome-wide SAR delivering desirable pathway effects R&D event highlighted ...

Furthermore, PNKP is involved in poly (ADP-ribose) polymerase 1 (PARP1)-dependent replication gap filling as part of a backup pathway in the absence of OFs ligation. Altogether, our data suggest that ...

CEP135 associates with SAS6 to link it to CPAP. Checkpoint kinase 1 (CHK1) phosphorylates and inhibits cell division cycle 25 (CDC25) A/C, which is responsible for dephosphorylating and activating ...

Generative Phosphoproteomics AP3 platform designed to enable streamlined, rational drug discovery, with proprietary, proteome-wide SAR delivering ...

4. Expansion opportunities: Success in endometrial cancer could pave the way for ACR-368’s use in other cancer types where the CHK1/2 pathway is implicated. 5. Combination potential: Acrivon’s ...

The AP3 platform is engineered to measure compound-specific effects on the entire tumor cell protein signaling network and ...

Cantor Fitzgerald also highlighted inquiries regarding the potential for an accelerated approval pathway based on the ... ACR-368, specifically targeting CHK1/2i, and ACR-2316, aimed at WEE1 ...