Abstract: The following sections are included: Introduction Compound Categories Natural products and derivatives Primary metabolites, co-substrates, co-factors, and marketed drugs Peptides and peptido ...

Kubinyi, H. Chemogenomics in drug discovery. Ernst Schering Res. Found. Workshop 58, 1–19 (2006). Article CAS Google Scholar Hopkins, A. L. Network pharmacology: the next paradigm in drug discovery.

Traditional folk medicine practices in China, Hong Kong, Japan and Korea – all located in Northeast Asia – are comparable. Since different usage of a herbal medicine may reflect cultural or regional ...

Jupyter Notebook 0 GPL-3.0 0 0 0 Updated on Dec 2, 2024 CARAMeL Public Condition-specific Antibiotic Regimen Assessment using Mechanistic Learning MATLAB 1 GPL-3.0 0 0 0 Updated on Jul 24, 2024 ...

We present the development and application of a new machine-learning approach to exhaustively and reliably identify major histocompatibility complex class I (MHC-I) ligands among all 208 octapeptides ...

Of great interest in recent years has been computationally predicting the novel polypharmacology of drug molecules. Here, we applied an “induced-fit” protocol to improve the homology models of 5-HT2A ...

A multidisciplinary journal that focuses on drug discovery and the development lifecycle, from the identification of drug entities to the design and development of new candidate medications and the ...

3.3 Changes in protein expression profiles in response to chitosan Cell growth and morphological analysis indicated that chitosan with concentration of 0.05% (w/v) could exert effective inhibition on ...