Currently, their roles in modulating CD8 T-cell effector and memory differentiation are unclear. Here, we report that developing CD8 T cells lacking Tet1/3 preferentially differentiate into ...

Before each cell division, termed mitosis, the genetic information must first be duplicated. This ensures that each chromosome in the cell that is ready to divide receives two copies of genetic ...

Mechanistic Insights: The study offers valuable mechanistic insights into the development of microcephaly by elucidating the role of Abba in radial glial cell proliferation, radial fiber organization, ...

(E) Images of ER-FlucDM-eGFP aggregates surrounded by the ER membrane in a MCF10A cell. Single Z-slice images were shown. (F) TEM images of sectioned MCF10A interphase cells expressing ER-FlucDM-eGFP.

Specifically, TKIs target tyrosine kinases – enzymes that normally regulate cellular growth, survival, and differentiation but, when dysregulated, drive unchecked cell division and tumor formation.

Berubicin showed clinically relevant outcomes comparable to Lomustine across multiple endpoints, but not a statistically significant difference in overall survival, the primary endpoint.

For successful cell division, chromosomal DNA needs to be ... that we see in the shape the genome takes in interphase and mitosis under the microscope." ...

To prepare the 46 chromosomes of a human cell for transport to the daughter cells during cell division ... shape the genome takes in interphase and mitosis under the microscope." ...

Scientists at EMBL have captured how human chromosomes fold into their signature rod shape during cell division, using a groundbreaking method called LoopTrace ... the vast differences that we see in ...