This disrupts the translation initiation complex and provides degradative enzymes with access to the 5′ cap and remaining RNA body. The intimate relationship between mRNA decay and translation ...

With this method, they can monitor individual ribosomes as they convert mRNA into proteins. The researchers discovered that ribosomes help each other when encountering difficulties, a process they ...

This detection scheme ensures that mRNA that is cap-less, tail-less, or fragmented will not be detected, enabling a measurement of only the fully intact mRNA in a single assay. The kit is provided ...

You can expect three times the transcriptional yield (4 mg/mL) and a much-improved capping efficiency (>95%) over traditional methods. The mRNA cap structure is an important point of consideration for ...

View Full Profile. Learn about our Editorial Policies. During translation, multiple ribosomes travel along the nucleic acid chain to build polypeptides that become functional proteins. Occasionally, ...

Dr. Vinod Balachandran says mRNA vaccines could stimulate the immune system to recognize and attack pancreatic cancer cells. An experimental approach to treating pancreatic cancer with the messenger ...

According to the terms of the agreement, TriLink will supply its patented CleanCap® M6, CleanCap® AG 3’OMe, CleanCap® AG, and CleanCap® AU cap analogs for use in Aldevron’s mRNA ...