Lung cancer (LC) is a major global health issue, with high mortality rates and limited therapeutic options. It is primarily categorized into non-small cell lung cancer (NSCLC) and small cell lung ...

Lung cancer (LC) is a major global health issue, with high mortality rates and limited therapeutic options. It is primarily categorized into non-small ...

The tiny strings of RNA promote translation of a protein implicated in cancer, a hint they could ... that miRNAs were found to enhance gene expression. A paper published in Science in 2007 pointed to ...

The following is a summary of "Epigenetic-modification associated hnRNPA3 acts as a prognostic biomarker and promotes malignant progression of HCC," published in the April 2025 issue of BMC Cancer by ...

Combined serum CA19-9 and miR-27a-3p in peripheral blood mononuclear cells to diagnose pancreatic cancer. Cancer Prev ... The evaluated study examined the miRNA profiles in peripheral blood ...

Through the mouse model, the researchers found that a cluster of miRNAs, labeled miRNA 290-295 in mice, were exclusively expressed and secreted by undifferentiated testicular cancer cells.

Malignant testicular germ cell tumors are the most common cancers diagnosed in males ages 15 to 39 in the U.S., though incidence has increased by almost 40% in the last 50 years. At the same time, ...

See how small bits of non-coding RNA target mRNA for destruction and regulate gene expression ... The mRNA targets of miRNA can be determined by using bioinformatics methods and bioassays for ...

Early-onset CRC (EO-CRC) was associated with Flavonifractor plautii and increased bile acid, tryptophan, and choline ...

Their work, published in Advanced Science ("Targeted DNA Nanomachine Enables Specific miRNA-Responsive Singlet Oxygen ... Confocal imaging and qPCR confirmed that microRNA-7 expression was about six ...

TCGA was a decade-long, National Cancer Institute-led effort to ... a million models across six categories—gene expression, DNA methylation, miRNA, copy number, mutation calls and multi-omics ...

Moreover, circRNAs primarily operate as competitive endogenous RNAs (ceRNAs), effectively "sponging" miRNAs and thereby ...