Malignant testicular germ cell tumors are the most common cancers diagnosed in males ages 15 to 39 in the U.S., though ...
Colorectal cancer is a serious but preventable disease if detected early. Advances in diagnostics, such as biomarker analysis ...
Brian Tait, Chief Scientific Officer at Haplomic Technologies Pty Ltd, focuses here on CYP genes, haplotypes, and their ...
Researchers have validated a specific cluster of microRNAs (miRNAs) as reliable biomarkers for detecting malignant testicular ...
头颈部鳞状细胞癌(HNSCC)预后差且治疗面临诸多难题。为探究糖酵解和乳酸代谢相关基因(GALMRGs)对 HNSCC 的影响,研究人员开展相关研究。结果发现 16 个差异表达基因,构建的预后模型能有效分层患者,还识别出两种分子亚型。该研究为 HNSCC 个性化治疗提供新方向。
为解决结直肠癌(CRC)治疗难题,研究人员开展了 miRNA-431-5p 对 KLK6 在 CRC 中靶向作用的研究。通过生物信息学分析及细胞实验,发现 miR-431-5p 可靶向 KLK6,这为 CRC 治疗提供了潜在新途径,对临床治疗意义重大。
RNA-based therapeutics are gaining traction due to advancements in delivery technologies, despite historical challenges with ...