本研究针对HPV16与沙眼衣原体共感染促进宫颈癌的分子机制不明问题，揭示了HPV16 E6和C. trachomatis Pgp3蛋白通过上调Daxx表达，激活MDM2-p53通路抑制TNF-α诱导的细胞凋亡，为共感染协同致癌提供了新靶点。 宫颈癌作为全球女性第四大 ...

Genetic variations in C. trachomatis enable the pathogen to evade and survive the host immune response, compete with other bacteria or grow in a suitable environment within the host; while genetic ...

Genetic Variation in C. trachomatis. A number of chlamydial virulence factors, such as the chlamydial protease activity factor (CPAF/CT858) and the GroEL (CT110)–GroES (CT111) operon, apparently ...

Chlamydia – caused by the organism Chlamydia trachomatis – caused an estimated 128.5 million new infections in 2020, according to the World Health Organization (WHO), with a global prevalence ...

Researchers began homing in on treatments that were specific to hepatitis C itself in 2011. The results were two protease inhibitors (PIs) called boceprevir (Victrelis) and telaprevir (Incivek).

Montana Governor Greg Gianforte (R) and other business executives sat down for a discussion on the home-building industry at the Reagan National Economic Forum in Simi Valley, California. The ...

Emerging evidence suggests a potential connection between chronic STIs and an elevated risk of male cancers, particularly ...

Charles C. W. Cooke is a senior editor at National Review and the host of The Charles C. W. Cooke Podcast. I don’t have questions for the thoroughly absurd Zohran Mamdani. I have questions for ...

Upon infection by an intracellular pathogen, host cells activate apoptotic pathways to limit pathogen replication. Consequently, efficient proliferation of the obligate intracellular pathogen ...