They found a new molecule named lariocidin —a potential new antibiotic with the power to kill some of the world’s most ...

Although structure-based drug discovery is still ... the binding of the antibiotics rifampicin and myxopyronin to bacterial RNA polymerase 86,87. These structures are helpful not only for ...

In the process, DNA is transcribed into RNA and then translated into functional proteins that subsequently undergo folding to achieve their correct structure, which is key to proper function.

Nick Blackmer is a librarian, fact-checker, and researcher with more than 20 years of experience in consumer-facing health and wellness content. New research suggests that bacterial vaginosis, a ...

PA protein is one subunit of the polymerase of influenza viruses and plays a critical role in its life cycle ... releasing the viral genome into the cytoplasm. RNA Release and Transcription: The ...

All are broad-spectrum antibiotics used to treat many different types of bacterial illness. When the E. coli biofilms were on microplastics, they grew dramatically faster, larger and more ...

Awareness of RNA-based therapies has increased after the widespread adoption of mRNA vaccines against SARS-CoV-2 during the COVID-19 pandemic. These mRNA vaccines had a significant impact on reducing ...

A team led by Professor Kazuhiro Maeshima of the National Institute of Genetics (ROIS) and SOKENDAI in Japan has developed a method to visualize different types of chromatin and reveal their ...

Bacterial H-NS forms nucleoprotein filaments that spread on DNA and bridge distant ... In this study, we report that bridged H-NS filaments strongly increase pausing by E. coli RNA polymerase at a ...

and then recruits other enzymes that eventually degrade the complex formed by the different RNA molecules. Previous research has shown that six Hfq subunits combine to form a ring-shaped structure and ...