Emerging evidence suggests that autophagy plays a crucial role in regulating and fine-tuning cGAS-STING signaling. Reciprocally, cGAS-STING pathway members can actively induce canonical as well as ...

Apoptosis and cell cycle in melanoma cell lines A375 and A2058 were assessed via flow cytometry. Western blot analysis was performed to examine autophagy and associated signaling proteins, while ...

Dr. Weickert will present Pacylex at the OBIO® Investment Summit and Early Technology Showcase February 5-7, 2025, at the Arcadian Court & Loft, Toronto Mr. Kamdar will present Pacylex at the PWMC ...

The protein Spns1 helps transport fat molecules out of lysosomes, preventing harmful buildup and offering insights for rare ...

These trends could be reversed through removing half of the MPs in DF-O. Therefore, dust fall microplastics inhibited autophagy and induced apoptosis via activating the PI3K/Akt/mTOR pathway, ...

Accumulation of fat molecules is detrimental to the cell. Researchers from the Yong Loo Lin School of Medicine, National ...

"In Purkinje cells, ATG5 actively regulates metabolic pathways to prevent cell death." Professor Dr. Kononenko added, "These findings highlight the sophisticated ways autophagy supports neuronal ...

Plants droop and shed their leaves when parched, but with a splash of water, their stems regain strength and their leaves ...

7 refine our understanding of the signaling effects of oncogenic KRAS. Rather than activating multiple effectors, mutant KRAS signals preferentially through the RAF–MEK–ERK pathway ...