Astrocytes play a fundamental role in synapse formation, pruning, and plasticity, which are associated with learning and memory. However, the role of astrocytes in learning and memory is still largely ...

Brain astrocytes and microglia causes excessive removal of synapses at the early stage of stroke. Inhibition of their phagocytosis improved neurobehavioral outcomes. Long-term post-stroke cognitive ...

Astrocytes are the largest and most prevalent type of glial cell in the central nervous system. Astrocytes contribute to formation of the blood–brain barrier, participate in the maintenance of ...

These non-neuronal cells include astrocytes, microglia, and oligodendrocytes, which through regulating brain homeostasis, structural stability, and trophic support, play a key role in maintaining ...

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More information: Katlin H. Zent et al, Synapse-to-nucleus ERK-CREB transcriptional signaling requires dendrite-to-soma Ca2+propagation mediated by L-type voltage-gated Ca2+channels, The Journal ...

Using high-tech spatial transcriptomics, they identified that neuronal IL-1R1 regulates gene pathways involved in synapse organization without triggering typical inflammation ... ventricular ependymal ...

Between the axon of a transmitting neuron and the dendrite of a receiving neuron is a gap called the synapse—the site at which signals are passed between the brain cells. The nervous system ...