Investigation of the constituents of Pycnanthus angolensis roots has resulted in the isolation of four new cyclolignene derivatives, named pycnanthulignene A (1), pycnanthulignene B (2), ...

EAT based on an antipseudomonal β-lactam drug as monotherapy (ceftazidime or cefepime, meropenem or imipenem, or piperacillin-tazobactam) or as combination therapy (with an aminoglycoside, ...

Colistin use was restricted when the potentially less-toxic aminoglycosides and other antipseudomonal agents became available. As a result, ...