Antigen-presenting cells (APCs) are a heterogeneous group of immune cells that mediate the cellular immune response by processing and presenting antigens for recognition by certain lymphocytes ...

Acellular Artificial Antigen-presenting Cells. Acellular artificial antigen-presenting cells (aAPCs) are micro- or nano-particle-based reductionist systems that mimic the biological cues given by ...

Researchers have found that antigen-specific killer T cells (CD8+ T cells) rapidly expand in the lungs when primed by antigen-presenting lung-resident alveolar macrophages (AMs). This interaction ...

Preliminary scientific report. Jennifer Connors, David Joyner, Nathan Mege, et al. Lipid nanoparticles (LNP) induce activation and maturation of antigen-presenting cells in young and aged ...

Chimeric antigen receptor (CAR) T cells are engineered to boost or hijack a person’s immune system to target their cancer. Besides being equipped with CARs that target specific antigens, T cells ...

But a study published yesterday (September 15) in Nature Cell Biology suggests that an interaction between T cells and antigen presenting cells (APCs) early in the immune response to viruses may ...

Although the mRNA COVID-19 vaccines from Pfizer-BioNTech and Moderna are safe and effective at preventing severe illness in adults and children, including immunocompromised individuals ...

Antigen-presenting cells express proteins on their surface to activate cytotoxic T cells, which kill infected cells. A recent paper in Nature Immunology by a Germany-based group outlined the ...

Immune cells produce IFNγ in a range of infectious and other sickness conditions, and scientists have detected interferon-response microglia in models of neurodegeneration and in the AD brain (Mathys ...

Antigen-presenting cells rally T cells to the scene, launching an attack on the foreign tissue. These are the first steps of organ transplant rejection.

Thetis Cells Train the Immune System To Tolerate Helpful Outsiders. Thetis cells are a type of antigen-presenting cell, whose job is to present foreign substances (antigens) to other immune cells.

Antigen-presenting cells must educate the immune system. These cells provide signals that tell the immune system to attack foreign bacteria and viruses — or instruct it to tolerate harmless proteins ...