为探究循环激素和蛋白质组与肌萎缩侧索硬化症（ALS）的因果关系，明确潜在治疗靶点，研究人员开展孟德尔随机化（MR）研究。结果发现，遗传预测的较高游离睾酮（FT）水平与 ALS 风险降低 23% 相关，12 种血浆蛋白与 ALS 存在因果关联。这为 ALS 防治提供了新方向。

此次研究成果发表在《InFo Neurologie + Psychiatrie》杂志上，为该领域的研究提供了重要的参考。它提醒医学界，在面对复杂的神经退行性疾病如 ALS 时，不能局限于传统的单一药物治疗模式，联合疗法或许能为患者带来更多的生存希望和更好的生活质量。随着研究的不断深入，相信未来会有更多针对 ALS 的有效治疗方法问世，帮助患者摆脱病痛的折磨。

Trethera Corporation (“Trethera”), a clinical stage biopharmaceutical company committed to targeting cancer and autoimmune ...

An American neurologist and an Italian epidemiologist whose work revolutionized the treatment of multiple sclerosis on ...

An American neurologist and an Italian epidemiologist whose work revolutionised the treatment of multiple sclerosis yesterday ...

Damage to the genetic material of mitochondria – the mitochondrial DNA or mtDNA for short – can lead to diseases such as Parkinson's, Alzheimer's, amyotrophic lateral sclerosis (ALS), cardiovascular ...

At one point during her health journey, Chandler resident Erin Kienlen thought she had amyotrophic lateral sclerosis, or ALS.

announced clinical results from treating a patient with ALS (amyotrophic lateral sclerosis, also known as Lou Gehrig’s disease) with TRE-515 under the FDA Expanded Access program. TRE-515 ...

About Amyotrophic Lateral Sclerosis Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is a progressive, inflammatory neurodegenerative disease impacting nerve cells in the ...

LOS ANGELES, March 31, 2025 (GLOBE NEWSWIRE) -- Trethera Corporation ("Trethera”), a clinical stage biopharmaceutical company committed to targeting cancer and autoimmune diseases through ...

Damage to the mitochondria, the “power plants” of the cells, contributes to many diseases. Researchers from Heinrich Heine ...

Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is a progressive, inflammatory neurodegenerative disease impacting nerve cells in the brain and spinal cord, reducing ...