资讯
为探究细胞质 β - 和 γ-actin 同工型及非肌肉肌球蛋白 2(NM2)同工型在调节膜皮层力学和连接组织中的作用,研究人员以 MDCK 等上皮细胞为对象开展研究。结果发现 γ-actin 缺失会引发一系列变化,该研究揭示了相关生物力学回路,对理解上皮细胞功能意义重大。
An actin monomer in solution has a conformation that's a little wider than when it's part of a longer actin polymer. The previous model, said Zsolnay, assumed that the wide shape transitions into ...
Vesicle‐Associated Actin Assembly by Formins Promotes TGF β ‐Induced ANGPTL4 Trafficking, Secretion and Cell Invasion. Advanced Science , 2023; 2204896 DOI: 10.1002/advs.202204896 Cite This ...
The actin filaments in this so-called HeLa cell are labeled in red/orange, and the movement you see represents the dynamic, ever-changing nature of these filaments within the cell. The GI-SIM ...
The rheometer and confocal microscopes clearly visualized the fluorescently labeled actin network and they filmed the polymer filaments'movement in 3-D when mechanical stress was applied.
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