Apoptosis and autophagy constitute the two self-destructive processes by which supernumerary, damaged or aged cells and organelles are eliminated. Beyond this homeostatic function, autophagy is ...

Therapeutic intervention with MAGL inhibitors slows down fibrosis progression and reverses established fibrosis. In vivo and in vitro, anti-inflammatory and antifibrogenic effects of MAGL inhibitors ...

In flies defective for axonal transport of mitochondria, the authors report the upregulation of one subunit, the beta subunit, of the heterotrimeric eIF2 complex via mass spectroscopy proteome ...

Autophagy is an evolutionarily conserved mechanism of cell adaptation to metabolic and environmental stress. It mediates the disposal of protein aggregates and dysfunctional organelles, although ...

This month's cover highlights the article DNA damage response at telomeres boosts the transcription of SARS‐CoV‐2 receptor ACE2 during aging by Sara Sepe, Francesca Rossiello, Fabrizio d’Adda di ...

Neuroinflammation and autophagy dysfunction are closely related to the development of neurodegeneration ... The sources for primary antibodies were listed as follows: anti-β-actin, anti-p62, ...