New serine biomarkers show promise for early Alzheimer's detection, linking tau assemblies to cognitive decline and offering ...

Researchers say CSF biomarker test correlates with the severity of cognitive decline, independent of other factors, including brain amyloid deposition.

Other pathological events, such as Aβ-mediated neurotoxicity ... Advances in our understanding of the mechanisms of tau-mediated neurodegeneration in Alzheimer's disease (AD) and related ...

Traumatic brain injury (TBI), Alzheimer’s disease (AD), and epilepsy share proposed mechanisms of injury ... However, due to (1) sustained UPR signaling interacting with tau and Aβ (2) the inability ...

Development of Prediction Model for Brain Amyloid-Beta Accumulation for Early Screening of Alzheimer's Disease MACHINE LEARNING MODEL USING ...

Enter SynPull, a new synaptosome imaging method developed by David Klenerman, John Danial, and colleagues at the University of Cambridge, England. SynPull combines single-molecule pull-down of ...

augmenting the link between Aβ and Aβ, reducing the clearance of some excess protein aggregates, and promoting the pathological formation of Tau protein. NLRP3, nucleotide-binding domain leucine-rich ...

Sweden Background Alzheimer's disease (AD) pathology is found in a considerable portion of patients with Parkinson's disease (PD), particularly those with early dementia (PDD). Altered cerebrospinal ...

Researchers found that COVID-19 may accelerate biological processes linked to Alzheimer’s, showing changes in brain-related ...

Prolonged rapid eye movement latency may be a potential marker for Alzheimer disease and Alzheimer disease and related dementias.