The decision to terminate the HYPERION trial reflects a loss of clinical equipoise, making it unethical to continue the placebo-controlled study.

AGEP can closely mimic generalized pustular psoriasis (GPP), requiring histopathologic confirmation and assessment of peripheral eosinophilia.

Patients with ATTR-PN have a high rate of comorbidities and substantial direct healthcare and economic burdens, a study found.

Associations between therapies and quality of life (QoL) in patients with generalized pustular psoriasis (GPP) can differ substantially.

The phase 1 trial is testing the safety tolerability, pharmacokinetics, and pharmacodynamics of PVT201 in healthy volunteers and patients.

The original Rai system classification was divided into 5 stages from 0 to IV. The updated system now divides the disease into 3 stages 3: ...

Daily supplementation of beta-hydroxy-beta-methylbutyrate (HMB) could improve overall daily activity in Duchenne muscular dystrophy (DMD), a study found.

Chronic lymphocytic leukemia (CLL) is the most common adult leukemia in Western countries. It is characterized by the progressive accumulation of mature-appearing yet immunologically dysfunctional B ...

Surgical resection significantly improved overall survival and cancer-specific survival in primary central nervous system lymphoma (PCNSL).

A little more than a third (36.1%) of patients with Huntington disease (HD) and chorea are taking an anti-chorea medication, a study found.

Multiple steps are involved in the pathogenesis of chronic lymphocytic leukemia (CLL) and various factors are related to its development: cytogenetic aberrations, antigenic triggers activated by ...

EGPA-associated nasal polyposis should be managed with medically (ie, biologics, anti-inflammatory drugs, and topical corticosteroids) and, in some cases, surgery. Nasal polyposis associated with ...