Background and aims: Cyclooxygenase 2 (COX-2) is upregulated in most colorectal cancers and is responsible for metabolism of the endogenous cannabinoid, anandamide, into prostaglandin-ethanolamides ...

Background Steatotic liver disease-related hepatocellular carcinoma (SLD-HCC), a rising global challenge, is characterised by ...

Objective To appraise the evidence that pathophysiological mechanisms and individualised treatment directed at those mechanisms provide an alternative approach to the treatment of patients with ...

We read with great interest the study published by Boxhoorn et al , comparing lumen-apposing metal stents (LAMS) versus double-pigtail plastic stents (DPPS) for treatment of infected necrotising ...

We read with great interest the recent article by Tseng et al evaluating hepatitis B surface antigen (HBsAg) levels as a ...

The suitability and tolerability of oats has been a long-standing controversy in the management of coeliac disease (CD). In ...

8 European Foundation for the Study of Chronic Liver Failure (EF CLIF), Barcelona, Spain Background Acute-on-chronic liver failure (ACLF) of various aetiologies is a complex syndrome with high ...

The integration of advanced endoscopy within the practice of hepatology is nowadays heralded in the concept of ‘endohepatology’ and is dichotomised in applications intervening for disorders of the ...

Background: Helicobacter pylori infection induces progressive inflammatory changes in the gastric mucosa that may lead to gastric cancer. Understanding long term effects resulting from the cure of ...

Objective The incidence of early-onset colorectal cancer (EO-CRC) is steadily increasing. Here, we aimed to characterise the interactions between gut microbiome, metabolites and microbial enzymes in ...

Background Metabolic dysfunction-associated steatotic liver disease (MASLD) affects over 30% of the general population and is the fastest growing cause of hepatocellular carcinoma (HCC). Current ...

Background Neutrophil infiltration and hepatocyte damage are indispensable hallmarks in alcohol-associated hepatitis (AH), yet the underlying crosstalk between neutrophils and hepatocytes and its role ...