Individual genes express multiple mRNAs by pre-mRNA alternative splicing, alternative polyadenylation or use of alternative promoters (first exons). As a result, individual genes express multiple ...

How can only 25,000-30,000 protein-coding genes in humans produce the massive variety of proteins, cells, and tissues that exist in our bodies? The answer: alternative splicing. A critical finding ...

leading to alternative splicing and different mature mRNA variants. 1 Alternative splice sites tend to be suboptimal allowing for modulation by RBPs. At the posttranscriptional level, nonsense ...

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Announcing a new publication for Acta Materia Medica journal. Single-cell RNA sequencing (scRNA-seq) data from published ...

Announcing a new publication for Acta Materia Medica journal. Single-cell RNA sequencing (scRNA-seq) data from published datasets were obtained to investigate the expression and dysregulation of ...

Single-cell RNA sequencing (scRNA-seq) data from published datasets were obtained to investigate the expression and ...

The idea that speckles might be storage sites for spliceosomes triggered Guttman to look deeper into how nuclear organization might affect the splicing process. In a recent article, he showed that ...

When a self-cleaving ribozyme is embedded in the mRNA, the spontaneous self-cleavage of ribozyme leads to destruction ... Transcription-induced RNA mutations include chimeric RNA, alternative splicing ...