Researchers have identified a key role microglia play in melanoma brain metastases progression and mechanisms to target them.

Brain metastases are one of the most severe complications of melanoma, the most aggressive type of skin cancer. Researchers at the Institute for Neurosciences (IN), a joint center of the Spanish ...

Researchers at University of Tsukuba have discovered a novel mechanism involved in brain development. They found that small fragments called micronuclei produced by neuronal nuclei are released into ...

The study, published today in Cancer Cell, demonstrates that microglia, a type of resident immune cell in the brain, can be manipulated to reduce brain metastases growth and enhance immunotherapy ...

They also found that microglia, which are resident immune cells in the brain, incorporate these micronuclei, thereby altering gene expression patterns and microglial characteristics. The brains of ...

Pexidartinib or PLX3397 is an enzyme inhibitor commonly used to remove microglia in the lab setting to help researchers better understand the role of these cells in brain health, function ...

Wu and colleagues confirmed that cultured-microglia-carrying lipid droplets struggled with phagocytosis, poorly engulfing ...

Xenon is one of the six noble gases. Its name derives from the Greek word for “strange”. In medicine, it has been used as an anaesthetic since the early 1950s and, more recently, to treat brain ...

Researchers at Texas A&M University College of Medicine have developed a new therapy that may slow the progression of ...

Researchers have found that a lifelong diet rich in choline could help protect against Alzheimer’s disease. Choline is an ...