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此外,星形胶质细胞是大脑微环境中的主要神经胶质细胞,与神经元紧密接触。以往研究表明,肿瘤细胞可通过与星形胶质细胞相互作用来增强其在脑部的定植能力,但脑转移癌细胞是否能通过分泌 gaba 来 “驯化” 星形胶质细胞,进而营造有利于肿瘤细胞生存的微环境,这一问题也有待解答。
全生命周期 gaba 变化趋势:通过非参数全生命周期模型发现,在大约 80 岁之后,年龄相关的皮质 gaba 差异的斜率趋于平缓。 这意味着,在认知健全的高龄老人中,大脑皮质 GABA 的变化在 80 岁之后不再随着年龄增长而显著变化。
Asynchronous GABA release generates long-lasting inhibition at a hippocampal interneuron-principal neuron synapse. Nat Neurosci 2005; 8 : 1319–28. Article CAS Google Scholar ...
Home » GABA Inhibition Could be Avenue for Stroke Rehabilitation. X. Upgrade your daily dose of biopharma and medtech news. Subscribe to BioWorld™ news services. See subscription options. To read the ...
Gamma-aminobutyric acid (GABA), the primary inhibitory chemical messenger in the brain, ... they prevented the recruitment of GABA-mediated inhibition and extinction of fear.
More information: Stefanie Heba et al. Local GABA Concentration Predicts Perceptual Improvements After Repetitive Sensory Stimulation in Humans, Cerebral Cortex (2015).DOI: 10.1093/cercor/bhv296 ...
Scientists have shed new light on the role of GABA, a key signaling molecule in the brain. Researchers have delved into how GABA's levels in the brain are regulated and its broader impacts on ...
Getting on 'the GABA receptor shuttle' to treat anxiety disorders Date: December 1, 2009 Source: Elsevier Summary: There are increasingly precise molecular insights into ways that stress exposure ...
Experimentally increasing the activity of a subclass of nerve cells that produce the neurotransmitter gamma-aminobutyric acid (GABA) has antidepressant effects similar to pharmaceutical ...
Gail Mick, M.D. Photography: Lexi Coon For the first time, humans with newly diagnosed Type 1 diabetes, or T1D, have received two treatments called GABA and GAD that have shown promise in animal ...
Second, Mechanism of Tonic GABA Current Inhibition: There was a misconception in the literature that inhibition of tonic GABA currents was mediated by hyperpolarization, ...
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