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Fluorogenic probe to detect enzyme linked to early stage of Alzheimer’s . Indian Institute of Science (IISc) Journal Analytical Chemistry DOI 10.1021/acs.analchem.3c00099. Keywords ...

Get Instant Summarized Text (Gist) A dimethylpiperidine-based cross-linker, DPST, enables one-step enrichment and quantitative analysis of protein complexes in living cells, minimizing sample loss ...

The probe combines a fluorophore and a zinc-binding region. It fluoresces only when it binds to both zinc atoms in the enzyme active site. In the presence of inhibitors that block the active site ...

Neutrons probe oxygen-generating enzyme for a greener approach to clean water. ScienceDaily. Retrieved June 2, 2025 from www.sciencedaily.com / releases / 2017 / 11 / 171113195004.htm.

The team's probe works by detecting an enzyme that is released in large quantities during IPHs, called heme oxygenase-1 (HO-1). Previous attempts to screen for HO-1 have been unreliable and cannot ...

Neutrons probe oxygen-generating enzyme for a greener approach to clean water Peer-Reviewed Publication. DOE/Oak Ridge National Laboratory ...

But as the probe comes into contact with HO-1, the enzyme breaks a bond connecting these two compartments, and causes a build up of the fluorescent molecules in the donor compartment.

Elena A. Goun of the University of Missouri and coworkers have developed a bioluminescent probe to measure BSH activity in a variety of settings, including in bacteria, fecal samples, and live ...

In another experiment, in mice, the team used the probe to test the ability of different types of prebiotic supplement — inulin and fructo-oligosaccharides (FOSs) — to boost the production of BSH.

It is now possible to obtain three-dimensional, high-resolution images of enzyme activity in tissue samples or whole organs—thanks to probe molecules that anchor fluorescent dyes within tissue ...