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Fluorogenic probe to detect enzyme linked to early stage of Alzheimer’s . Indian Institute of Science (IISc) Journal Analytical Chemistry DOI 10.1021/acs.analchem.3c00099. Keywords ...

The probe combines a fluorophore and a zinc-binding region. It fluoresces only when it binds to both zinc atoms in the enzyme active site. In the presence of inhibitors that block the active site ...

A fluorescent probe lights up the enzyme beta-galactosidase in a cell culture. The glowing probe-enzyme combination could make tumors fluoresce, allowing surgeons to cut away cancer while leaving ...

Elena A. Goun of the University of Missouri and coworkers have developed a bioluminescent probe to measure BSH activity in a variety of settings, including in bacteria, fecal samples, and live ...

It is now possible to obtain three-dimensional, high-resolution images of enzyme activity in tissue samples or whole organs—thanks to probe molecules that anchor fluorescent dyes within tissue ...

Neutrons probe oxygen-generating enzyme for a greener approach to clean water Peer-Reviewed Publication. DOE/Oak Ridge National Laboratory ...

In addition to indicating the presence of the NDM enzyme, the florescent chemical probe developed by Que and Walt Fast, a professor of chemical biology and medicinal chemistry, may help find a ...

Neutrons probe oxygen-generating enzyme for a greener approach to clean water. ScienceDaily. Retrieved June 2, 2025 from www.sciencedaily.com / releases / 2017 / 11 / 171113195004.htm.

But as the probe comes into contact with HO-1, the enzyme breaks a bond connecting these two compartments, and causes a build up of the fluorescent molecules in the donor compartment.

In another experiment, in mice, the team used the probe to test the ability of different types of prebiotic supplement — inulin and fructo-oligosaccharides (FOSs) — to boost the production of BSH.