The patient was diagnosed with hereditary ATTR-CM following genetic testing, which revealed the presence of a mutation in the TTR gene. Researchers from India and the US presented the case of a ...

This case demonstrates that isolated optic neuritis in CLL can be effectively managed with corticosteroids and close monitoring, potentially avoiding the need for immediate systemic therapy. The ...

Factors such as ECOG score and methotrexate response more strongly predicted progression-free and overall survival than epilepsy status in PCNSL. Epilepsy in patients with primary central nervous ...

Patients in the intervention group showed a significant reduction in the Beck Depression Inventory-II scores and stability in markers of disease progression. Reducing levels of depression in older ...

A case has been reported of anti-CD19 chimeric antigen receptor (CAR)-T cell therapy inducing complete remission in a patient with immunosuppressive therapy (IST)-resistant acquired hemophilia A (AHA) ...

FGFR3-related conditions may be conceptualized as a continuous disease spectrum, rather than a collection of discrete clinical diagnoses. Although achondroplasia and hypochondroplasia are considered ...

Given that sleep apnea patterns vary over the first years of life, age-specific interpretation of sleep studies may be essential. Significant heterogeneity in obstructive apnea hypopnea index (OAHI) ...

Patients with PNH on complement inhibitors are at an increased risk of meningococcal infections and should be appropriately monitored. A teenage girl with a diagnosis of paroxysmal nocturnal ...

The alterations correlated with poorer extremity motor function, and further analysis revealed a link between disrupted lipid metabolism and MS severity. Patients with multiple sclerosis (MS) have ...

The core care team for TK2d may include a neuromuscular neurologist, pulmonologist, nutritionist, physical therapist, and orthopedist. A pulmonologist monitors and manages respiratory complications.

Single-cell RNA sequencing revealed heightened immune activation in patients with alloimmunized SAA, paralleling immune responses seen in FNAIT. HLA class I alloimmunization in severe aplastic anemia ...

When ofatumumab became available, the team decided to switch the treatment from natalizumab, given the lower risk profile reported for ofatumumab. A new case report from Japan details the experience ...