The investigation of children with early developmental impairment (EDI) is challenging in terms of selecting investigations and supporting families through the diagnostic pathway. Modern genomic ...

CK, creatine kinase; DAT, direct antiglobulin test; EMA, antiendomysial antibody; LDH, lactate dehydrogenase.; TSH, thyroid stimulating hormone; tTG, tissue ...

Determining severity of illness and undertaking an adequate risk assessment is a fundamental part of acute paediatric practice. This review highlights physiology, communication, heuristics and ...

Table 2 Advantages and barriers of using continuous glucose monitoring ...

Signs and symptoms of anorexia nervosaTable 1 Signs and symptoms of anorexia nervosa ...

Next generation sequencing (NGS), massively parallel or deep sequencing are related terms that describe a DNA sequencing technology which has revolutionised genomic research. Using NGS an entire human ...

Electronic data are increasingly recorded in clinical practice. Just as advances in genetics have gradually led to clinical benefit1 so too are ‘big data’ bringing tangible advances to patient care.2 ...

Figure 1 Relationship between thoughts, feelings, physical symptoms and behaviours.

Clustered regularly interspaced palindromic repeats (CRISPR)/Cas9 is a gene-editing technology causing a major upheaval in biomedical research. It makes it possible to correct errors in the genome and ...

Table 1 Approximate costs for commonly used investigations in children with chronic abdominal pain ...

The digital world continues to evolve and is apparent in all aspects of daily life. For children and young people, their online life is as real to them as their in-person life. Health professionals ...

Figure 5 Blood film showing small lymphocytes with hyperchromatic, cleaved nuclei.