Modeling of the E. coli 30S ribosome. Two types of approaches are implemented to model E. coli 16S rRNA structure. For regions where the sequences are aligned without deletion or insertion, direct ...

Figure 1: Cryo-electron microscopic structure of programmed 70S ribosome (RNC) with signal sequence. Figure 3: Transfer of signal sequence from the ribosome to SRP. Figure 4: Mammalian SRP bound ...

The model used a random sequence with noise and an empty protein structure simultaneously but gradually refined the sequence and the structure for more accuracy, better predictions, and lower noise.

Neo-1 is the first model to unify de novo molecular generation and atomic-level structure prediction in a single model, by generating latent representations of whole molecules instead of ...

Bridging this gap requires a model that can integrate biological sequence input with structural constraints defined by G4 topological formalism. Objectives of the research: To develop a hybrid AI ...