The sequence of amino acids in the chain determines how the chain will fold up to make the protein, so different proteins have different three-dimensional shapes. The three-dimensional shape of a ...

The large subunit rRNA, in particular, is responsible for the peptidyl transferase reaction, which catalyzes the formation of peptide bonds between amino acids during protein synthesis. This discovery ...

This process of protein synthesis occurs in two stages - transcription and translation. When a gene is to be expressed, the base sequence of DNA is copied or transcribed into mRNA (messenger RNA).

Their study, published in Nature Cell Biology, shows that a protein called Serrate connects RNA modification and microRNA production, two essential cellular functions, in a way previously unknown.

Biologists have discovered a new type of RNA-splicing regulation that helps to determine which protein-coding exons will be included in messenger RNA transcripts. RNA splicing is a cellular ...